Effect of Pinus massoniana Lamb. bark extract on lytic cycle of Epstein-Barr virus.

نویسندگان

  • Shuxia Xu
  • Shimin Zhang
  • Xuedong Wang
  • Yaqian Gao
  • Xing Qin
  • Kun Wu
چکیده

Pinus massoniana bark extract (PMBE) at a concentration of 60 microg/mL or more inhibits the expression of Epstein-Barr virus (EBV) lytic proteins, such as Rta, Zta, and EA-D. EBV lytic cycle was blocked by inhibiting the transcription of immediate-early genes. The results suggest that the PMBE has anti-EBV activity. Thus, the extract is potentially useful in preventing the lytic development of EBV in vitro.

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عنوان ژورنال:
  • Indian journal of experimental biology

دوره 50 10  شماره 

صفحات  -

تاریخ انتشار 2012